SiBioLead offers client-based services for various cutting-edge computational biology techniques. We provide end-to-end project-based services for both academic and commercial entities for a reasonable price. We have a dedicated team of trained bioinformatics experts, and cloud-based High-Performance Computing support to perform various high-demand computational biology tasks.
High-throughput virtual screening (HTVS) enables rapid, low-cost screening of significantly larger small molecule datasets, like ChemBridge or ChEMBL database, than feasible in experimental screenings.
Highlights of our HTVS service
Kinase profiling is crucial for identification of selective and potent kinase inhibitors. Determining selectivity of kinase inhibitors play a vital role in the novel drug discovery process. Experimental kinase profiling of large number of lead candidates is time consuming. Our virtual kinase profiling reduces time and effort, at the same time is cost effective. We have developed an automated protocol for structure-based kinome-wide virtual screening of target small molecules and our protocol is lauded by many of our clients.
Highlights of Kinome-wide virtual screening
Molecular dynamic simulations provide useful insights into understanding protein biology and mechanism of action. MD simulations can be applied to visualize large to subtle conformational changes in proteins pertaining to its activity. For our clients, we perform microsecond-scale molecular dynamics simulations of target molecular systems. Our expert bioinformatics team, based on project requirements, provides a complete set of results analysis for MD simulation trajectories.
Categories of MD simulations
We offer competitive pricing plans
USD $30 per target/library for high-throughput virtual screen.
USD $80 per simulation up to 300 nanosecond.
For more information on our service and pricing plans, request a quote/estimateGet a Quote